Lisa Akiyama

Feb 12, 2024 | onlinelibrary.wiley.com | Samuel W. Terman |Laura E. Kirkpatrick |Lisa Akiyama |Wadih Baajour

This review discusses the latest drugs and devices in the epilepsy diagnostics and therapeutics pipeline. Many antiseizure medications plus other genetic and nongenetic therapeutics are currently under development, including many that are first-in-class. Seizure tracking, detection, and stimulation devices all continue to make advances as devices enter the pipeline. 1 INTRODUCTION The need remains for innovation in epilepsy diagnostics and treatments.

Dec 22, 2023 | onlinelibrary.wiley.com | Samuel W. Terman |Laura E. Kirkpatrick |Wesley T. Kerr |Lisa Akiyama

Substantial efforts are underway towards optimizing the diagnosis, monitoring, and treatment of seizures and epilepsy. We describe preclinical programs in place for screening investigational therapeutic candidates in animal models, with particular attention to identifying and eliminating drugs that might paradoxically aggravate seizure burden.