Livia Delpiano

Mar 29, 2024 | biorxiv.org | Tabata Apablaza |SANDRA Villanueva |Marisol Barros-Poblete |Livia Delpiano

AbstractThe respiratory tract possesses a highly regulated innate defense system which includes efficient cilia-mediated mucus transport or mucociliary clearance (MCC). This essential process relies on appropriate hydration of airway surfaces which is controlled by a blend of transepithelial sodium and liquid absorption via the epithelial sodium channel (ENaC), and anion and liquid secretion, primarily regulated by the cystic fibrosis transmembrane conductance regulator (CFTR) channel.