Longzhi Li

Sep 25, 2023 | onlinelibrary.wiley.com | Han Xu |Longzhi Li |Bing Dong |Ji Lu

1 INTRODUCTION In breast cancer, which is the most frequent malignancy in women,1 triple-negative breast cancer (TNBC), detected as negative expression of estrogen receptor (ER), progesterone receptor (PR), and epidermal growth factor receptor 2 receptor (HER2) by immunohistochemistry, is easy to relapse and metastasize.2 Given a lack of effective endocrinotherapy and molecular targeted therapy, the main treatment option is chemotherapy for TNBC.3, 4 However, TNBC patients usually develop...