Lora T. Mcglade

4 weeks ago | francais.medscape.com | Lora T. Mcglade

Entre 50 et 60 % des adultes ont des crampes nocturnes dans les jambes qui induisent, chez 20 % d’entre eux, une insomnie et un sentiment de détresse. Or, il n’existe pas de médicaments à la fois sûrs et efficaces. Le magnésium et les inhibiteurs calciques ont un bénéfice limité, la quinine davantage mais avec un risque d’effets secondaires notables.

Jan 8, 2025 | mdedge.com | Lora T. Mcglade

TOPLINE:Among 57,086 older adults, new gabapentin users demonstrated lower fall-related healthcare visits than duloxetine users, with a weighted cumulative incidence of 84.44 vs 158.21 per 1000 person-years at 180 days. Incident gabapentin use showed a 48% lower hazard of falls at 6-month follow-up, with no increase in severe fall-related events.  METHODOLOGY:Researchers conducted a new user, active comparator cohort study using IBM MarketScan Research Databases from January 2014 to December 2021.

Dec 28, 2024 | medscape.com | Lora T. Mcglade

Analysis revealed muscle-building supplement users had higher odds of initiating anabolic-androgenic steroid use by the next survey wave than nonusers.

Dec 10, 2024 | mdedge.com | Lora T. Mcglade

TOPLINE:The association persists even after accounting for adverse pregnancy outcomes. Women who have experienced infertility without fertility treatment show a 25% higher risk for systemic autoimmune rheumatic disease (SARD) up to 9 years after delivery, compared with those without infertility. METHODOLOGY:Population-based cohort study analyzed 568,053 singleton births among 465,078 women aged 18-50 years without pre-existing SARD in Ontario, Canada, from 2012 to 2021.

Dec 10, 2024 | mdedge.com | Lora T. Mcglade

TOPLINE:Among pregnant patients with chronic hypertension, delivery at 39 weeks of gestation provides an optimal balance between stillbirth risk and neonatal outcomes. Analysis of 227,977 term singleton deliveries shows consistent findings across different patient subgroups. METHODOLOGY:A population-based retrospective cohort study analyzed 227,977 nonanomalous singleton term births in the United States from 2014 to 2018 among patients with chronic hypertension.