Lori B. Chibnik

Jan 7, 2025 | onlinelibrary.wiley.com | Yining Hua |Andrew Beam |Lori B. Chibnik |John Torous

1 INTRODUCTION The integration of Large Language Models (LLMs) into psychiatry and mental health research is poised to revolutionize the field by enhancing diagnostic accuracy, personalizing care, and streamlining administrative tasks (Hua et al., 2024; Obradovich et al., 2024; Zhou et al., 2023). LLMs can efficiently process vast amounts of data, summarize clinical notes, and assist in complex decision-making processes (Yu et al., 2023).

Feb 25, 2024 | nature.com | Andrew Ratanatharathorn |Karestan C. Koenen |Lori B. Chibnik

AbstractResearch has suggested that mental illness may be a risk factor for, as well as a sequela of, experiencing intimate partner violence (IPV). The association between IPV and mental illness may also be due in part to gene-environment correlations.

Nov 30, 2023 | nature.com | Hyun-Sik Yang |Vilas Menon |Hilary Finucane |Hans-Ulrich Klein |Lori B. Chibnik |Julie Schneider | +1 more

AbstractMany of the Alzheimer’s disease (AD) risk genes are specifically expressed in microglia and astrocytes, but how and when the genetic risk localizing to these cell types contributes to AD pathophysiology remains unclear. Here, we derive cell-type-specific AD polygenic risk scores (ADPRS) from two extensively characterized datasets and uncover the impact of cell-type-specific genetic risk on AD endophenotypes.

Jun 16, 2023 | onlinelibrary.wiley.com | Andrea Roberts |Andrew Ratanatharathorn |Lori B. Chibnik |Laura D. Kubzansky

Distress-related psychosocial factors Five distress-related psychosocial factors were measured repeatedly over follow-up, including depression, anxiety, social isolation, widowhood, and, in a subset of participants, PTSD.