Luis E Gonzales-Huerta

2 weeks ago | biorxiv.org | Thomas Williams |James Griffiths |Luis E Gonzales-Huerta |David Bell

AbstractIt is estimated that in excess of 10 million people around the globe are affected by severe asthma and fungal sensitisation (SAFS) or allergic bronchopulmonary aspergillosis (ABPA), severe asthma endotypes driven by hypersensitivity to environmentally ubiquitous fungal pathogens, primarily Aspergillus fumigatus. Here, we sought to define the immunological pathways underlying these allergic fungal airway diseases.