Maike G. Sweegers

Jul 25, 2024 | nature.com | Martina Schmidt |Helene Rundqvist |Joachim Wiskemann |Jana Annina Müller |Maike G. Sweegers |Carlo Fremd | +6 more

AbstractPhysical exercise both during and after curative cancer treatment has been shown to reduce side effects. Evidence in the metastatic cancer setting is scarce, and interventions that improve health-related quality of life (HRQOL) are much needed for patients with metastatic breast cancer (MBC). The multinational randomized controlled PREFERABLE-EFFECT trial assessed the effects of exercise on fatigue and HRQOL in patients with MBC.

Mar 8, 2023 | bmjopen.bmj.com | Maike G. Sweegers |Alina Vrieling |Helene Rundqvist |Emine Akdemir

Methods and analysisThe ENHANCE study is a multicentre, open label, two-arm randomised controlled trial. Patient inclusion and data collection started in August 2022. Ethical approval, extending to all participating centres, was granted by the Medical Ethical Committee NedMec (Amsterdam, The Netherlands), under reference number 22–595/NL78792.031.22. The trial is prospectively registered in Clinical Trials on 29 July 2022.