Máire Ní Leathlobhair

Oct 26, 2024 | nature.com | Máire Ní Leathlobhair |Anna Frangou |Ben Kinnersley |Alex J. Cornish |Eszter Lakatos |Andreas Gruber | +10 more

AbstractTesticular germ cell tumours (TGCT), which comprise seminoma and non-seminoma subtypes, are the most common cancers in young men. In this study, we present a comprehensive whole genome sequencing analysis of adult TGCTs. Leveraging samples from participants recruited via the UK National Health Service and data from the Genomics England 100,000 Genomes Project, our results provide an extended description of genomic elements underlying TGCT pathogenesis.