Malgorzata E. Rogalska

Oct 31, 2024 | science.org | Jerika J. Barron |Zhenyu Wang |Roberto Arbore |Malgorzata E. Rogalska

Editor’s summaryNucleated cells have evolved a complex molecular machinery to remove internal sequences known as introns from the primary RNA transcripts of genes. This splicing process is necessary for the translation of gene messages into proteins and allows the production of alternative mRNAs and proteins from individual genes. After individually lowering the expression of more than 300 genes encoding components of the intron-removing machinery, Rogalska et al.