Manoj Medapati

Mar 17, 2024 | mdpi.com | Nisha Singh |Ben Ulmer |Manoj Medapati |Christine Zhang

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Jan 20, 2024 | biorxiv.org | Nisha Singh |Robert J. Schroth |Ben Ulmer |Manoj Medapati

AbstractMacroautophagy (hereafter autophagy) is a lysosomal degradation pathway that functions in nutrient recycling and as a mechanism of innate immunity. Previously we reported, a novel host-bacteria interaction between cariogenic S. mutans and bitter taste receptor (T2R14) in gingival epithelial cells (GEC) leading to an innate immune response. Further, S. mutans might be using the host immune system to inhibit other Gram-positive bacteria, such as S. aureus.