Mar De Miguel

Madrid

Staff Writer at BioWorld

Staff Writer at BioWorld Science

Biologist & Science Writer @BioWorld @Clarivate. Contributor @elmundociencia Music lover, cofounder @JungleIndieRock

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Articles

Stem cell therapies show safety in clinical trials in Parkinson's

1 week ago | bioworld.com | Mar De Miguel

Stem cell therapies show safety in clinical trials in Parkinson'sStem cell implantation is a step closer to becoming the next strategy against Parkinson's disease. Two clinical trials, one in phase I and the other in phase I/II, have demonstrated their safety and potential to restore dopamine production in the brains of patients with this currently incurable neurodegenerative condition.
Commander proteins linked to lysosomal dysfunction in Parkinson’s

1 week ago | bioworld.com | Mar De Miguel

Neurology/psychiatricCommander proteins linked to lysosomal dysfunction in Parkinson’sGenes associated with lysosomal dysfunction increase the risk of Parkinson’s disease (PD), according to a study led by scientists at Northwestern University. The discovery also explains why some people who carry a pathogenic variant of the GBA1 gene develop PD or dementia with Lewy bodies (DLB) and others do not. The key lies in the Commander complex, involved in the transport of proteins to this organelle.
Mouse brain structure and function shown on high-resolution map

1 week ago | bioworld.com | Mar De Miguel

Neurology/psychiatricMouse brain structure and function shown on high-resolution mapScientists from the Machine Intelligence from Cortical Networks (MICRONS) consortium have published the microconnectome of a cubic millimeter of the mouse brain. This is the most complete map of this organ to date at nanometer resolution for a mammal.
First atlas of the endometrium with polycystic ovary syndrome

2 weeks ago | bioworld.com | Mar De Miguel

Women's healthFirst atlas of the endometrium with polycystic ovary syndromeAlthough the causes of polycystic ovary syndrome (PCOS) are unclear, researchers know this condition leads to endometrial dysfunction in women who have hormonal imbalances, and insulin resistance.
Ten days of normal survival of a pig liver in a human being

3 weeks ago | bioworld.com | Mar De Miguel

Drug design, drug delivery & technologiesTen days of normal survival of a pig liver in a human beingTransplanting an animal organ into a human is now a closer reality following the successful xenotransplantation of a genetically modified pig liver into a patient diagnosed with brain death in China. The operation was intended to evaluate organ function over a 10-day period. This is a complex experimental trial that did not involve removing the patient's liver and still requires further study.
Dissecting the role of neural circuits in mental health

3 weeks ago | bioworld.com | Mar De Miguel

Neurology/psychiatricDissecting the role of neural circuits in mental healthIn the brain, molecular information is transmitted between cells through neural circuits. Synapses establish connections between the pathways that run from one area to another, allowing the most complex organ in the body to fulfill different functions. Cells and neural circuits are the basic biological elements in the study of mental illness.
Ten days of normal survival of a pig liver in a human being

3 weeks ago | bioworld.com | Mar De Miguel

Drug design, drug delivery & technologiesTen days of normal survival of a pig liver in a human beingTransplanting an animal organ into a human is now a closer reality following the successful xenotransplantation of a genetically modified pig liver into a patient diagnosed with brain death in China. The operation was intended to evaluate organ function over a 10-day period. This is a complex experimental trial that did not involve removing the patient's liver and still requires further study.
Ten days of normal survival of a pig liver in a human being

4 weeks ago | bioworld.com | Mar De Miguel

Drug design, drug delivery & technologiesTen days of normal survival of a pig liver in a human beingTransplanting an animal organ into a human is now a closer reality following the successful xenotransplantation of a genetically modified pig liver into a patient diagnosed with brain death in China. The operation was intended to evaluate organ function over a 10-day period. This is a complex experimental trial that did not involve removing the patient's liver and still requires further study.
AI-based spatial omics unveils molecular talks in tumors

1 month ago | bioworld.com | Mar De Miguel

Drug design, drug delivery & technologiesAI-based spatial omics unveils molecular talks in tumorsThe three-dimensional analysis of cell types and their locations by spatial transcriptomics provides key information of their interactions within tissues or organs.
AI reads cancer cells’ 3D shape to predict their drug response

1 month ago | bioworld.com | Mar De Miguel

Drug design, drug delivery & technologiesAI reads cancer cells’ 3D shape to predict their drug responseScientists at the Institute of Cancer Research (ICR) in the U.K. are developing a technology that analyzes, in vitro, how the 3D morphology of cancer cells changes when exposed to a compound, using AI to predict their response to new treatments.