Marcus M. Weera

Dec 13, 2023 | jneurosci.org | Marcus M. Weera |Daniel Webster |Jason Middleton |Nicholas W. Gilpin

AbstractAvoidance stress coping, defined as persistent internal and/or external avoidance of stress-related stimuli, is a key feature of anxiety- and stress-related disorders, and contributes to increases in alcohol misuse after stress exposure.

Oct 27, 2023 | jneurosci.org | Marcus M. Weera |Daniel Webster |Jason Middleton |Nicholas W. Gilpin

Traumatic stress-induced increases in anxiety-like behavior and alcohol self-administration are mediated by central amygdala CRF1 neurons that project to the lateral hypothalamus Marcus M. Weera, Daniel A. Webster, Rosetta S. Shackett, Federica Benvenuti, Jason W. Middleton, Nicholas W. Gilpin Journal of Neuroscience 6 November 2023, JN-RM-1414-23; DOI: 10.1523/JNEUROSCI.1414-23.2023

Aug 5, 2023 | nature.com | Marcus M. Weera |Nicholas W. Gilpin

The central amygdala (CeA) modulates affective states and adaptive behaviors, under both normal and pathological conditions. Rodent studies show that cells in the CeA express a variety of neuropeptides and neuropeptide receptors that modulate the activity of CeA cells. The neuropeptide corticotropin-releasing factor (CRF) and CRF type-1 receptors (CRF1) are densely expressed in the CeA [1].