María Peña-Chilet

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Articles

Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments - Virology Journal

Oct 6, 2023 | virologyj.biomedcentral.com | Carlos Loucera |Rosario Carmona |Marina Esteban-Medina |Dolores Muñoyerro-Muñiz |Román Villegas |María Peña-Chilet | +2 more

This study uses a retrospective cohort which includes Andalusian patients with COVID-19 diagnosis, hospitalized during the period January 2020 to November 2021. The Ethics Committee for the Coordination of Biomedical Research in Andalusia approved the study (29th September, 2020, Acta 09/20) and waived informed consent for the secondary use of clinical data for research purposes.
Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models

Sep 29, 2023 | mdpi.com | María Peña-Chilet |Carlos Loucera |Marina Esteban-Medina |Miriam Payá-Milans

4. DiscussionThe activity of signaling pathways on sarcoma samples has been analyzed to, on the one hand, find how the degree of signaling pathway activity affects overall patient survival and, on the other hand, discover the alterations in sarcoma samples in contrast to sarcomagenic non-diseased tissues.
A Comprehensive Analysis of 21 Actionable Pharmacogenes in the Spanish Population: From Genetic Characterisation to Clinical Impact

Apr 19, 2023 | mdpi.com | Rocío Núñez-Torres |Guillermo Pita |María Peña-Chilet |Daniel López-López

Open AccessArticle by Rocio Nunez-Torres 1,*, Guillermo Pita 1, María Peña-Chilet 2,3,4, Daniel López-López 2,3,4, Jorge Zamora 1, Gema Roldán 2, Belén Herráez 1, Nuria Álvarez 1, María Rosario Alonso 1, Joaquín Dopazo 2,3,4,5 and Anna Gonzalez-Neira 1,6,* 1 Human Genotyping Unit (CEGEN), Cancer Genetics Program, National Cancer Research Center (CNIO), 28029 Madrid, Spain 2 Computational Medicine Platform, Fundación Progreso y Salud (FPS), Hospital Virgen del Rocío, 41013 Sevilla, Spain 3...
Crosstalk between Metabolite Production and Signaling Activity in Breast Cancer

Apr 18, 2023 | mdpi.com | Cankut Cubuk |Carlos Loucera |María Peña-Chilet |Joaquín Dopazo

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