María Quintana

1 month ago | nature.com | Maria Quintana |María Quintana

AbstractStudies on aging have centered on two molecular pathways: CDK4/6 and insulin/mTORC1. These pathways are thought to influence aging through distinct mechanisms: mTORC1 by reprogramming systemic metabolism, and CDK4 through p16-mediated senescence and inflammatory signaling (SASP). Here, we investigate the connection between aging and CDK4 in Caenorhabditis elegans, an organism lacking both p16 and SASP. Using a conditional degradation system, we demonstrate that CDK-4 inhibition in C.

Mar 16, 2025 | nature.com | Mariona Nadal-Ribelles |Guillaume Lieb |Carme Mateu Solé |Maria Quintana |María Quintana |Antonin Morillon | +4 more

AbstractIn response to stress, cells activate signaling pathways that coordinate broad changes in gene expression to enhance cell survival. Remarkably, complex variations in gene expression occur even in isogenic populations and in response to similar signaling inputs. However, the molecular mechanisms underlying this variability and their influence on adaptive cell fate decisions are not fully understood.

Nov 29, 2024 | mdpi.com | Grant Johnson |Maria Quintana |María Quintana |Matthew M. Dolde |Jonathan T. Zaugg

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Jul 17, 2024 | letralia.com | Maria Quintana |María Quintana

Al grito de la chicharra María Moreno Quintana Poesía Editorial El Escriba Buenos Aires (Argentina), 2022 ISBN: 978-987-605-931-2 142 páginas la forma de la luna reflejo de una noche deshabitada vino a llevarse mi alma valle encantado levedad de este sur no afloja el paso pleno de certezas retorna al punto crucial para remontarla se agiganta supera el límite el cansancio de vidas pasadas traspasa su propio espejo a la espera de una visión lluvia torrencial antes de que suceda el estallido sin...

Mar 14, 2024 | dialnet.unirioja.es | Maria Quintana |María Quintana |González Quintana

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