Marianna Fontana

Nov 27, 2024 | radcliffecardiology.com | Harriette Van Spall |Marianna Fontana |Andrew Coats |Milind Y. Desai

Video Published: Views: 34 Likes: 0 Average (ratings) AHA Conference 2024 - Safety and efficacy outcomes of nexiguran ziclumeran (NTLA-2001) in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM). Dr Marianna Fontana (University College London, London, UK) joins us onsite at AHA Conference to discuss the findings from the nexiguran ziclumeran for ATTR-CM trial (NCT04601051).

Nov 20, 2024 | hcplive.com | Connor Iapoce |Marianna Fontana

A groundbreaking CRISPR-based gene-editing therapy has demonstrated early success in treating transthyretin amyloidosis cardiomyopathy (ATTR-CM), a progressive and often fatal disease that can lead to heart failure, according to late-breaking at the American Heart Association (AHA) Scientific Sessions 2024.

Nov 18, 2024 | hcplive.com | Marianna Fontana |Connor Iapoce

A decline in kidney function was common in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) and linked to an elevated likelihood of mortality, even after adjustment for relevant biomarkers, according to new data presented at the American Heart Association (AHA) Scientific Sessions 2024.

Jun 8, 2023 | inkl.com | Marianna Fontana

It is caused by a build-up of abnormal proteins, known as amyloids, in heart tissues and affects its function. Scientists from University College London (UCL) and the Royal Free Hospital performed medical tests on the men, aged 68, 76 and 82, after reports that their symptoms were improving. Scans showed amyloid protein deposits had cleared from their hearts.

May 19, 2023 | medscape.com | Scott Solomon |James L. Januzzi |Rodolphe Barrangou |Marianna Fontana

closePlease confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. Log outCancel The therapeutic landscape of heart failure is changing, especially with the discovery of new biomarkers and a deeper understanding of genetics and its potential role in disease treatment.