Marija Balic

Jan 6, 2025 | digitalcommons.library.tmc.edu | Yiqun Zhang |Fengju Chen |Marija Balic |Chad J. Creighton

BACKGROUND: The differential gene expression profile of metastatic versus primary breast tumors represents an avenue for discovering new or underappreciated pathways underscoring processes of metastasis. However, as tumor biopsy samples are a mixture of cancer and non-cancer cells, most differentially expressed genes in metastases would represent confounders involving sample biopsy site rather than cancer cell biology.

Nov 8, 2024 | biorxiv.org | Alexander Chang |Marija Balic |Rohit Bhargava |Tanner Bartholow

AbstractBreast cancer affects 1/8 of women throughout their lifetimes, with 90% of cancer deaths being caused by metastasis. However, metastasis poses unique challenges to research, as complex changes in the microenvironment in different metastatic sites and difficulty obtaining tissue for study hinder the ability to examine in depth the changes that occur during metastasis. Rapid autopsy programs thus fill a unique need in advancing metastasis research.