Marilena Cesari

Nov 13, 2024 | acsjournals.onlinelibrary.wiley.com | Jayesh Desai |Andrew Wagner |Irene García |Marilena Cesari

INTRODUCTION Tenosynovial giant cell tumor (TGCT) is a rare, nonmalignant mesenchymal tumor of the synovium, bursae, or tendon sheaths that is driven by overexpression of colony-stimulating factor-1 (CSF-1).1-3 Surgery is the primary treatment for patients with TGCT when complete tumor resection is feasible; however, given the high frequency of disease recurrence, particularly in the diffuse subtype, patients may benefit from systemic therapy when surgical options are limited.2, 4...