Mario Duque

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C1q in non-immune human serum has a non-redundant complement function towards clinical Mycobacterium tuberculosis complex strains

Nov 3, 2024 | biorxiv.org | Mario Duque |Maximilian Peter Goetz |EMILIE ROUSSEAU |Susanne Homolka

AbstractThe Mycobacterium tuberculosis complex (MTBC) includes three human-adapted species: Mycobacterium tuberculosis, Mycobacterium africanum, and Mycobacterium canettii. With their genetic diversity and inherent virulence, these bacteria interact with host factors to influence tuberculosis (TB) transmission and pathogenesis. A critical yet poorly understood aspect of the immune response in TB involves the role of the complement system.

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