Mark Watson

Oct 2, 2024 | biorxiv.org | Mark Watson |Bikem Soygur |Fei Wu |Pooja R Devrukhkar

AbstractA major aging hallmark is the accumulation of cellular senescence burden. Over time senescent cells contribute to tissue deterioration through chronic inflammation and fibrosis driven by the Senescence-Associated Secretory Phenotype (SASP). The human ovary is one of the first organs to age, and prominent age-related fibroinflammation within the ovarian microenvironment is consistent with the presence of senescent cells, but these cells have not been characterized in the human ovary.

Jun 18, 2024 | cell.com | Gabriela Sánchez |Mark Watson |Karina Carvalho

Highlights•Phosphatidylcholine/phosphatidylethanolamine (PC/PE) induce TGF-β signaling in monocytes•Bile acids (BAs) induce type I IFN in monocytes•Efficacy of dengue vaccine Butantan-TV003 requires a broad nAb response to all four serotypes•nAb response to Butantan-TV003 is associated with pre-vaccination levels of BAs and PC/PESummaryProtective immunity to dengue virus (DENV) requires antibody response to all four serotypes.

Aug 29, 2023 | leidos.com | Mark Watson

Public cloud service providers like Amazon, Microsoft and Google offer a smorgasbord of cloud services, from simple storage and compute through to AI capabilities. They make it easy for customers to move on-premises workloads into the cloud and reduce their up-front capital investment and the people management required to manage IT workloads. The cloud market has shown no signs of slowing, especially for SMEs focusing on business missions rather than management of on-premise IT environments.

Aug 18, 2023 | lactualite.com | Mark Watson

MÉXICO — L’ouragan Hilary a rapidement atteint la catégorie 4 au large de la côte pacifique du Mexique, vendredi, et pourrait toucher le sud de la Californie en tant que tempête tropicale dans les prochains jours. Si la trajectoire de l’ouragan se maintient, la Californie pourrait être confrontée à sa première tempête tropicale en 84 ans, ce qui, selon les météorologistes, pourrait provoquer des inondations majeures, des glissements de terrain et des tornades.