Martijn J Schuemie

Jan 8, 2025 | nature.com | Martijn J Schuemie

AbstractUsing administrative claims and electronic health records for observational studies is common but challenging due to data limitations. Researchers rely on phenotype algorithms, requiring labor-intensive chart reviews for validation. This study investigates whether case adjudication using the previously introduced Knowledge-Enhanced Electronic Profile Review (KEEPER) system with large language models (LLMs) is feasible and could serve as a viable alternative to manual chart review.

Mar 19, 2024 | onlinelibrary.wiley.com | Tara Anand |Fan Bu |Martijn J Schuemie |Marc A. Suchard

1 BACKGROUND Current guidance for specific first-line antihypertensive medication is limited, based largely on expert opinion due to lacking clinical trials comparing various medications and drug classes.1 Previously, Suchard et al.2 generated hazard ratios (HR) comparing risks for new initiators of different drug classes for various safety and effectiveness outcomes with evidence demonstrating better primary effectiveness and safety for the class of thiazides and thiazide-like diuretics,...