Mary C Farach-Carson

Aug 29, 2024 | digitalcommons.library.tmc.edu | Christian Wright |Stuart J Warden |Julia M. Hum |Mary C Farach-Carson

Purpose of review: In this review, we discuss the mechanism of action of gabapentinoids and the potential consequences of long-term treatment with these drugs on the musculoskeletal system. Recent findings: Gabapentinoids, such as gabapentin (GBP) and pregabalin (PGB) were designed as antiepileptic reagents and are now commonly used as first-line treatment for neuropathic pain and increasingly prescribed off-label for other pain disorders such as migraines and back pain.