Mary S. Matsui

Aug 21, 2023 | onlinelibrary.wiley.com | Angelica Ortiz |Hong Sun |Thomas Kluz |Mary S. Matsui

Objective It is well established that exposure of human skin to airborne pollution, particularly in the form of particulate matter sized 2.5 μm (PM2.5), is associated with oxidative stress, DNA damage and inflammation, leading to premature signs of skin aging. Because much of the damage results from oxidative stress, we examined the effects of a topical composition containing three antioxidants in an in vitro model system to assess the potential for amelioration of premature aging.