Masahiro Mitsuhashi

Aug 22, 2024 | nature.com | Masahiro Mitsuhashi |Satoko Ueno |Kaoru Isa |Jun C. Takahashi |Kenta Kobayashi |Ryosuke Takahashi

AbstractWhether and how the non-lesional sensorimotor cortex is activated and contributes to post-injury motor recovery is controversial. Here, we investigated the role of interhemispheric pathway from the contralesional to ipsilesional premotor cortex in activating the ipsilesional sensorimotor cortex and promoting recovery after lesioning the lateral corticospinal tract at the cervical cord, by unidirectional chemogenetic blockade in macaques.