Matthew A. Crane

Apr 29, 2024 | jamanetwork.com | Mariana P. Socal |Matthew A. Crane |Gerard F. Anderson

Active pharmaceutical ingredients (APIs) are a main component and a key determinant of the quality of prescription drugs.1 In 2014, 9% of drug shortages were attributed to the unavailability of APIs.2 In addition, APIs could potentially be linked to the 40% of shortages attributed to quality problems and the 30% caused by manufacturing delays and capacity issues.1,2 Few recent studies have examined the prevalence or characteristics of shortages due to APIs. As generic drugs constituted about...

Oct 6, 2023 | kevinmd.com | Jennifer Lynn |Clarissa C. Ren |Sara Hurley |Matthew A. Crane

There are no words more devastating than, “Our hands are tied” to a survivor reporting abuse and seeking some semblance of accountability from a larger institution. “The institution admitted no fault” is a close second. Picture this sequence: a trusted physician at a renowned academic medical center sees a patient at a vulnerable stage in her life for a regular appointment. As she is exposed for a standard physical exam, he sexually assaults her.

Jul 25, 2023 | kevinmd.com | Nicole Cifra |Clarissa C. Ren |Sara Hurley |Matthew A. Crane

There are a few clinical scenarios that stand out to me from my undergraduate medical education. I completed a combined MD/MPH program, and I remember coming back from the year of public health, inserted between years two and three of medical school, feeling rusty and often in the way. One conversation I’ll always remember is one I overheard between an attending on my family medicine rotation (my first rotation of my third year) and one of his patients, a woman in her sixties.

May 23, 2023 | jamanetwork.com | Matthew A. Crane |Michael J. DiStefano |Thomas Moore

Introduction Online direct-to-consumer (DTC) advertisements for prescription drugs, depending on context, are variously regulated by the US Food and Drug Administration, the Federal Trade Commission, and/or state consumer protection statutes.