Maximilian Wranik

Dec 2, 2023 | nature.com | Maximilian Wranik |Quentin Bertrand |Tobias Weinert |Antonia Furrer |Hannah Glover |Melissa Carrillo | +13 more

AbstractSerial crystallography at X-ray free-electron lasers (XFELs) permits the determination of radiation-damage free static as well as time-resolved protein structures at room temperature. Efficient sample delivery is a key factor for such experiments. Here, we describe a multi-reservoir, high viscosity extruder as a step towards automation of sample delivery at XFELs. Compared to a standard single extruder, sample exchange time was halved and the workload of users was greatly reduced.

Dec 2, 2023 | nature.com | Maximilian Wranik |Quentin Bertrand |Tobias Weinert |Antonia Furrer |Hannah Glover |Melissa Carrillo | +13 more

AbstractSerial crystallography at X-ray free-electron lasers (XFELs) permits the determination of radiation-damage free static as well as time-resolved protein structures at room temperature. Efficient sample delivery is a key factor for such experiments. Here, we describe a multi-reservoir, high viscosity extruder as a step towards automation of sample delivery at XFELs. Compared to a standard single extruder, sample exchange time was halved and the workload of users was greatly reduced.

Feb 17, 2023 | newsbreak.com | Maximilian Wranik

The binding and release of ligands from their protein targets is central to fundamental biological processes as well as to drug discovery. Photopharmacology introduces chemical ...