Mayuresh G Gadgil

1 week ago | biorxiv.org | Andrew Rice |Mayuresh G Gadgil |Paola Bisignano |Richard Stein

AbstractAmino acids undergo numerous enzymatic modifications. However, the broad applicability of amino acid-modifying enzymes for synthetic purposes is limited by narrow substrate scope and often unknown regulatory or accessory factor requirements. Here, we characterize ChlH, a flavin-dependent halogenase (FDH) from the chlorolassin biosynthetic gene cluster.