Mazal N Zebak

Nov 30, 2024 | biorxiv.org | Fang Li |Elise Duboscq Flynn |Philip Ha |Mazal N Zebak

AbstractTranslating human genomic discoveries into mechanistic insights requires linking genetic variations to candidate genes and their causal functional phenotypes. Genome-wide association studies have consistently identified LIPA as a risk locus for coronary artery disease (CAD), with previous expression quantitative trait loci (eQTL) analyses prioritizing LIPA as a candidate causal gene.