Mehdi Boroumand

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Accelerating Antibody Development: Sequence and Structure-Based Models for Predicting Developability Properties through Size Exclusion Chromatography

Feb 7, 2025 | biorxiv.org | Mehdi Boroumand |Isabelle Sermadiras |Jenna Caldwell |Valentin G. Stanev

AbstractExperimental screening for biopharmaceutical developability properties typically relies on resource-intensive, and time-consuming assays such as size exclusion chromatography (SEC). This study highlights the potential of in silico models to accelerate the screening process by exploring sequence and structure-based machine learning techniques.

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