Mengmeng Tai

Nov 26, 2024 | onlinelibrary.wiley.com | Tingting Hu |Yan Shen |Kaihan Wang |Mengmeng Tai

1 Introduction Familial hypercholesterolemia (FH) is one of the most prevalent, heritable diseases that disrupts lipid metabolism. The main clinical manifestations of FH include noticeably high level of low-density lipoprotein cholesterol (LDL-C), excessive cholesterol deposition in tissues, and premature atherosclerotic cardiovascular disease (ASCVD) (Defesche et al. 2017).