Micah A. Chrenek

1 week ago | mdpi.com | Nan Zhang |Ying Li |Xian Zhang |Micah A. Chrenek

4. Materials and Methods 4.1. Experimental DesignMice were divided into three groups: the Naïve group, the PBS+ONC group, and the TUDCA+ONC group. The Naïve group (12 mice) received no treatments. The PBS+ONC group (16 mice) received intraperitoneal (i.p.) injections of phosphate-buffered saline (PBS) and underwent unilateral optic nerve crush (ONC) surgery. The TUDCA + ONC group (15 mice) received i.p. injections of tauroursodeoxycholic acid (TUDCA) followed by unilateral ONC surgery.