Michael Dew

Apr 8, 2024 | scholarsarchive.byu.edu | Michael Dew

KeywordsHippocampus, Plasticity, Depotentiation, Mice, Neuroscience, Sex DifferencesAbstractSynaptic plasticity of excitatory hippocampal circuits is one of the primary cellular mechanisms of learning and memory. Synaptic plasticity is also implicated in many disease states such as depression, post-traumatic stress disorder, and Alzheimer disease. Long-term potentiation (LTP) is the plastic strengthening of synapses, while long-term depression (LTD) is the weakening of synapses.