Michael F. Vaezi

Sep 26, 2023 | onlinelibrary.wiley.com | Ronnie Fass |Michael F. Vaezi |Prateek Sharma |Rena Yadlapati

1 INTRODUCTION Non-erosive reflux disease (NERD), also known as symptomatic non-erosive gastro-oesophageal reflux disease (GERD), is characterised by episodic heartburn symptoms related to acid refluxate without endoscopically detectable damage to the oesophageal mucosa.1, 2 NERD affects 50%–70% of patients presenting with GERD-related symptoms and, as a chronic condition with recurring symptom episodes, it can have a profound effect on patients' well-being.1, 2 Patients with NERD have...