Michela Marini

Jan 22, 2025 | digitalcommons.library.tmc.edu | Fabio Stossi |PANKAJ SINGH |Michela Marini |Kazem Safari

KeywordsSingle-Cell Analysis, Humans, Software, Image Processing, Computer-Assisted, Reproducibility of Results, Cell Line, Phenotype, High-throughput screening, SoftwareAbstractPhenotypic profiling by high throughput microscopy, including Cell Painting, has become a leading tool for screening large sets of perturbations in cellular models. To efficiently analyze this big data, available open-source software requires computational resources usually not available to most laboratories.

Mar 26, 2024 | biorxiv.org | Fabio Stossi |Pankaj K. Singh |Michela Marini |Kazem Safari

AbstractPhenotypic profiling by high throughput microscopy has become one of the leading tools for screening large sets of perturbations in cellular models. Of the numerous methods used over the years, the flexible and economical Cell Painting (CP) assay has been central in the field, allowing for large screening campaigns leading to a vast number of data-rich images.