Michele Veldsman

Feb 1, 2024 | onlinelibrary.wiley.com | Michele Veldsman |Adam E. Handel |Saiju Jacob |Paul Maddison

Introduction Leucine-rich glioma-inactivated 1-antibody encephalitis (LGI1-Ab-E) is the commonest form of autoimmune encephalitis (AE) in adults and typically causes seizures, behavioural and cognitive impairment.1, 2 Early immunotherapy often effectively treats seizures and can halt cognitive decline.3 However, longer-term LGI1-Ab-E follow-up studies highlight a potentially severe spectrum of neuropsychological impacts.4, 5 Little is known about which of these impact on quality-of-life (QoL).