Mikhail Nikolaev

Jul 2, 2024 | nature.com | L. Francisco Lorenzo-Martín |Nicolas Broguiere |Jakob Langer |Mikhail Nikolaev |George Coukos

AbstractExisting organoid models fall short of fully capturing the complexity of cancer because they lack sufficient multicellular diversity, tissue-level organization, biological durability and experimental flexibility. Thus, many multifactorial cancer processes, especially those involving the tumor microenvironment, are difficult to study ex vivo.