Milton Maciel

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Microorganisms | Free Full-Text | A First in Human Clinical Trial Assessing the Safety and Immunogenicity of Two Intradermally Delivered Enterotoxigenic Escherichia coli CFA/I Fimbrial Tip Adhesin Antigens with and without Heat-Labile Enterotoxin with Mut

Nov 2, 2023 | mdpi.com | Mark S. Riddle |Milton Maciel |Steven Poole |Ramiro L. Gutiérrez

1. IntroductionDiarrheal diseases are a leading cause of morbidity and mortality worldwide with the greatest burden in children living in low- to middle-income countries (LMICs) [,,,]. Among the most common causes of infectious diarrhea in these populations is enterotoxigenic E. coli (ETEC) [,,,,,].

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