Mina Tadrous

Aug 7, 2024 | ajmc.com | Hsiao-Ching Huang |Daniel R. Touchette |Mina Tadrous |Glen T. Schumock |Saria S. Awadalla |Todd Lee

ABSTRACTObjectives: Adherence to medications is important for the management of chronic diseases. Although the proportion of days covered (PDC) is a common metric for measuring adherence, it may be insufficient to distinguish relevant differences in medication-taking behavior. Group-based trajectory models (GBTMs) have been used to better represent adherence over time.

Feb 13, 2023 | cmaj.ca | Kevin Schwartz |Jun Wang |Mina Tadrous |Bradley J. Langford

InterpretationWe found that the use of nirmatrelvir–ritonavir in Ontario between April and August 2022 was associated with a significant reduction in the odds of hospital admission from COVID-19 or all-cause death with a NNT of 62. Our findings were consistent across most strata of age, drug–drug interactions, vaccination status and comorbidities; however, the absolute risk reductions were substantially lower in younger patients and those at lower risk of severe COVID-19.