Mohammad Aslam Imtiaz

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Genome-Wide Association Study Meta-Analysis of Neurofilament Light (NFL) Levels in Blood Reveals Novel Loci Related to Neurodegeneration

1 month ago | digitalcommons.library.tmc.edu | Shahzad Ahmad |Mohammad Aslam Imtiaz |Aniket Mishra |Ruiqi Wang

AbstractNeurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood NfL levels could provide new insights into molecular mechanisms underlying neurodegenerative disorders.
Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration - Communications Biology

Sep 8, 2024 | nature.com | Shahzad Ahmad |Aniket Mishra |Marisol Herrera-Rivero |Joshua C. Bis |Myriam Fornage |Gennady V Roshchupkin | +13 more

AbstractNeurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood NfL levels could provide new insights into molecular mechanisms underlying neurodegenerative disorders.

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