Articles
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Jan 9, 2025 |
journalofinfection.com | MRC Unit |Zoe Limited
Keywordsongoing symptomatic CovidPost-Covid SyndromeSARS-CoV-2 vaccineInfluenza (Flu) vaccineSymptomResearch in contextEvidence before this studyThe PubMed database was searched for articles published form 01/12/2020 until 29/09/2022, with search criteria: “((Long COVID) OR (post-acute) OR (post-COVID) OR (ongoing-symptoms)) AND (vaccination) AND (symptoms)”, yielding 320 articles.
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Jan 1, 2024 |
bmcmedgenomics.biomedcentral.com | MRC Unit
Mendelian randomisation uses SNPs (i.e., single nucleotide polymorphisms – SNPS –) or common genetic variants as instrumental variables (IVs) for an exposure of interest, rather than using the observed phenotype, to examine whether the exposure (or liability to an exposure if it is binary) has an effect on an outcome of interest [4]. MR exploits the unique properties of common genetic variants and the fact that genes are randomly allocated from parents to offspring during gamete formation [5].
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Dec 4, 2023 |
trialsjournal.biomedcentral.com | MRC Unit
We will carry out a two-arm, single-blind, parallel-group, superiority RCT comparing the intervention group, receiving access to the ‘Live Well with Parkinson’s’ Toolkit to TAU with a 1:1 allocation, including a cost-effectiveness analysis and mixed methods process evaluation. This protocol paper focuses on the main clinical and cost-effectiveness RCT. A detailed protocol for the aligned process evaluation will be reported separately.
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Sep 14, 2023 |
frontiersin.org | Cape Town |Western Cape |MRC Unit
Simone R. Williams1, 2* Frances C. Robertson3, 4 Catherine J. Wedderburn1, 2, 5 Jessica E. Ringshaw1, 2 Layla Bradford1, 2 Charmaine N. Nyakonda1, 2 Nadia Hoffman6 Shantanu H. Joshi7 Heather J. Zar2, 8 Dan J. Stein1, 6, 9 Kirsten A.
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Jul 31, 2023 |
genomebiology.biomedcentral.com | MRC Unit
Study cohortsWe analysed data collected from 2478 samples across three different UK population cohorts, of which 2358 samples passed quality control assessment and are included in the analyses in this manuscript. TwinsUK [20] (post-QC \(n = 394\), from 236 unique families) is the UK’s most comprehensive and detailed registry of adult monozygotic and dizygotic twins.
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