Muthuswamy Raveendran

2 months ago | digitalcommons.library.tmc.edu | Luis F. Paulin |Muthuswamy Raveendran |R Harris |Jeffrey Rogers

BACKGROUND: Recent population studies are ever growing in number of samples to investigate the diversity of a population or species. These studies reveal new polymorphism that lead to important insights into the mechanisms of evolution, but are also important for the interpretation of these variations.

Jul 4, 2024 | nature.com | Meng Wang |R. Alan Harris |Muthuswamy Raveendran |Laura Young |David H. O’Connor |Michael J. Montague | +4 more

AbstractUnderstanding and treating human diseases require valid animal models. Leveraging the genetic diversity in rhesus macaque populations across eight primate centers in the United States, we conduct targeted-sequencing on 1845 individuals for 374 genes linked to inherited human retinal and neurodevelopmental diseases. We identify over 47,000 single nucleotide variants, a substantial proportion of which are shared with human populations.