Mutlu Arat

Mar 18, 2024 | nature.com | Romain Guièze |Johannes Schetelig |Jakob Passweg |Jürgen Finke |Mutlu Arat |Friedrich Stölzel | +7 more

AbstractManagement of Richter transformation (RT) is particularly challenging, with survival estimates <1 year. We report on outcomes of 66 RT patients undergoing allogeneic-HCT (allo-HCT) between 2008 and 2018 registered with the EBMT. Median age at allo-HCT was 56.2 years (interquartile range (IQR), 51.3–63.1). Median time from RT to allo-HCT was 6.9 months (IQR, 4.9–11) and 28 (42.4%) were in complete remission (CR).

May 15, 2023 | frontiersin.org | Xiao-Ping Xu |Mutlu Arat |Sinem Civriz Bozdag |Robert Chen

1. Introduction Perioperative allogeneic blood transfusion is often required in patients undergoing multilevel spinal fusion surgery, due to the complexity of the surgery and the high risk of intraoperative mass blood loss (1–3). Transfusion could solve the problems such as anemia and hypovolemia caused by bleeding profusely (4, 5). However, adverse blood transfusion reactions and lack of blood supply are still unavoidable.