Nan Hou

Jun 7, 2024 | nature.com | Qilong Li |Ning Jiang |Nan Hou |Liying Yu |Yixin Yang |Anni Feng | +8 more

AbstractHost immune responses are tightly controlled by various immune factors during infection, and protozoan parasites also manipulate the immune system to evade surveillance, leading to an evolutionary arms race in host‒pathogen interactions; however, the underlying mechanisms are not fully understood. We observed that the level of superoxide dismutase 3 (SOD3) was significantly elevated in both Plasmodium falciparum malaria patients and mice infected with four parasite species.