Nancy A. Melville

6 days ago | medscape.com | Nancy A. Melville

For patients with diffuse large B-cell lymphoma (DLBCL), the detection of circulating tumor DNA (ctDNA) following first-line treatment is independently predictive of disease recurrence and overall survival over 2 years, suggesting important prognostic value of the biomarker to improve upon standard assessment with PET-CT imaging.

1 week ago | medscape.com | Nancy A. Melville

In the treatment of newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL), patients who fail to achieve initial molecular response with the third-generation tyrosine kinase inhibitor (TKI) ponatinib following induction can nevertheless go on to achieve minimal residual disease (MRD) negativity — and at higher rates than the earlier generation TKI imatinib.

2 weeks ago | mdedge.com | Nancy A. Melville

FROM DDW 2025SAN DIEGO — In the ever-expanding options for colorectal cancer (CRC) screening, blood tests using precision medicine are becoming more advanced and convenient than ever; however, caveats abound, and when it comes to potentially life-saving screening measures, picking the optimal screening tool is critical. Regarding tests, “perfect is not possible,” said William M.

3 weeks ago | medscape.com | Nancy A. Melville

SAN DIEGO — In the ever-expanding options for colorectal cancer (CRC) screening, blood tests using precision medicine are becoming more advanced and convenient than ever; however, caveats abound, and when it comes to potentially life-saving screening measures, picking the optimal screening tool is critical. Regarding tests, “perfect is not possible,” said William M.

3 weeks ago | medscape.com | Nancy A. Melville

SAN DIEGO — The majority of colorectal cancers (CRCs) that emerge following a negative colonoscopy and polypectomy occur prior to recommended surveillance exams, and those cases are more likely to be at an advanced stage, according to new research. Of key factors linked to a higher risk for such cases, one stands out — the quality of the baseline colonoscopy procedure.