Nataly Stylianou

Dec 12, 2023 | biorxiv.org | Kenneth J O'Byrne |Nataly Stylianou |Ismail Sebina |Nicholas Matigian

AbstractObjectives: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus infection in pregnancy is associated with higher incidence of placental dysfunction, referred to by a few studies as a 'preeclampsia-like syndrome'. However, the mechanisms underpinning SARS-CoV-2-induced placental malfunction are still unclear. Here, we investigated whether the transcriptional architecture of the placenta is altered in response to SARS-CoV-2 infection.