Nathan Grellier

Oct 7, 2024 | onlinelibrary.wiley.com | Nathan Grellier |Saint-Antoine Paris France |Julien Kirchgesner

We fully agree with the conclusions presented in the editorial by Drs. Pillay and Christensen [1], on our work (the ERIC study) [2], which emphasised the importance of early surgical intervention in certain cases of Crohn's disease (CD). We also believe that surgery should always be discussed in an integrated way for complicated CD but also for pure inflammatory ileal CD given the findings of the LIR!C trial [3, 4].

Sep 5, 2024 | onlinelibrary.wiley.com | Nathan Grellier |CRSA Sorbonne Université |Julien Kirchgesner |Mathieu Uzzan

1 INTRODUCTION Crohn's disease (CD) is a lifelong inflammatory disease affecting an increasing number of patients worldwide.1, 2 All segments of the gastrointestinal tract can be affected. The disease is limited to the terminal ileum in about one-third of the patients at diagnosis with a non-stricturing and non-penetrating disease for most of them.3 However, about 20% of patients have a complicated disease at diagnosis that may lead to early surgery.