Nathan Jensen

1 month ago | biorxiv.org | Nathan Jensen |Anna Goldstein |Keith Ly |Quentin Devaud

AbstractObjective. PRIMA subretinal implants provide prosthetic vision in patients blinded by age-related macular degeneration, with acuity closely matching the sampling limit of the pixel pitch: a single 100 μm pixel per line of a letter corresponds to 20/420 acuity. Decreasing the pixel size in the same flat geometry is difficult due to the constrained electric field, especially considering a 40 μm thick debris layer separating the implant from the target neurons.

Jul 30, 2024 | biorxiv.org | Nathan Jensen |Zhijie Chen |Anna Goldstein |Daniel Palanker

AbstractModeling of Multi-Electrode Arrays used in neural stimulation can be computationally challenging since it may involve incredibly dense circuits with millions of interconnected resistors, representing current pathways in an electrolyte (resistance matrix), coupled to nonlinear circuits of the stimulating pixels themselves.