Neil T. Kallgren

2 months ago | cell.com | Clare Booth |Brian Stevens |Clover A. Stubbert |Neil T. Kallgren |Ennis Deihl |Erin Davies

KeywordsregenerationplanarianSchmidtea polychroaembryogenesisaxial polarityWnt pathwayβ-cateninnotumwnt-1transcriptional injury responseIntroductionRegeneration encompasses tissue replacement strategies underlying the maintenance of form and function during homeostasis and the restoration of missing structures after injury. Regenerative abilities vary widely across metazoans.

Jul 23, 2024 | biorxiv.org | Brian Stevens |Erin Davies |Clover A. Stubbert |Neil T. Kallgren

AbstractFew studies have investigated whether or how regenerative abilities vary across developmental stages of animal life cycles. Determining mechanisms that promote or limit regeneration in certain life cycle stages may pinpoint the most critical factors for successful regeneration and suggest strategies for reverse engineering regenerative responses in therapeutic settings.