Nellie Chen

Jan 17, 2025 | digitalcommons.library.tmc.edu | John Steele |Ying Lin |Nellie Chen

Keywords: valproate, valproic acid, neural tube defect, antiseizure medication, anticonvulsant, antiepileptic, epilepsyAbstractValproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy and a variety of other neurological disorders. While VPA and other ASMs are efficacious for management of seizures, they also increase the risk for adverse pregnancy outcomes, including neural tube defects (NTDs).