Nerea Iragorri

Oct 29, 2024 | ehu.eus | Josebe Hurtado |Nerea Iragorri |Efraim Reyes |Jose L. Vicario

El grupo liderado por el catedrático de la UPV/EHU José Luis Vicario ha desarrollado una metodología para desimetrizar ciertas moléculas y obtener un tipo de asimetría molecular que abre la puerta a nuevas estructuras sin precedentes en la naturaleza y que podrían utilizarse como agentes terapéuticos. La revista Angewandte Chemie se hace eco de este descubrimiento y de la aportación que hace a una de las teorías relacionadas con el origen de la vida.

Oct 23, 2024 | ehu.eus | Josebe Hurtado |Nerea Iragorri |Efraim Reyes |Jose L. Vicario

The vast majority of organic molecules (based on a carbon structure) are not flat, they have a three-dimensional geometry. Various results can be obtained depending on the way the atoms are arranged inside each molecule. In some cases, a molecule and its mirror image may have completely different properties; we are talking about two symmetric molecules that have the same relationship that an object has with its image in a mirror.

Jul 26, 2024 | onlinelibrary.wiley.com | Josebe Hurtado |Nerea Iragorri |Efraim Reyes |Jose L. Vicario

Introduction The stereoselective generation of chiral molecular entities remains at the central core of research in organic synthesis due to the crucial role played by chirality in molecules that interfere in biological processes or drug discovery platforms.1 The three-dimensional shape affects the macroscopic properties of chiral compounds, to the extent that each enantiomer of a chiral drug can exhibit reduced or even deleterious effects based on their relative stereochemistry.

Jul 26, 2024 | pericles.pericles-prod.literatumonline.com | Elena Fernandez |Elena Fernández |Josebe Hurtado |Efraim Reyes |Nerea Iragorri

Cu-catalyzed asymmetric allylic borylation of 3,3’-disubstituted 1-vinylcyclobutan-1-ols renders axially chiral allylborane systems, with high asymmetric induction for both enantiomers, by precise selection of the cis or trans substrate.