Newby LK

Dec 4, 2024 | academic.oup.com | Newby LK

This comment refers to ‘Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery Disease’, which was presented at ESC Congress 2024 in London and simultaneously published in The New England Journal of Medicine, https://doi.org/10.1056/NEJMoa2407362. • None The Edoxaban vs.

Jun 5, 2024 | academic.oup.com | Newby LK

Thirty years ago, the Antiplatelet Trialists’ Collaboration published the first individual participant data (IPD) overview of 145 randomized trials of prolonged antiplatelet therapy for prevention of death, myocardial infarction (MI), and stroke (vascular events) in various categories of patients.1 The most widely tested antiplatelet regimen was ‘medium dose’ (75–325 mg/day) aspirin, and the Antiplatelet Trialists’ Collaboration found no evidence that either a higher aspirin dose or any other...

May 25, 2024 | academic.oup.com | Newby LK

Cardiovascular diseases (CVDs) pose a significant global health threat [1–3]. These conditions, encompassing heart attacks, strokes, and hypertension, contribute to a substantial number of annual deaths and disabilities [1, 3]. One particularly concerning aspect of CVDs is their asymptomatic nature.

May 22, 2024 | karger.com | Luis Manuel |Newby LK

Background: Preservation of organ function and viability is a crucial factor for survival in cardiogenic shock (CS) patients. There is not information enough on cytoprotective substances that may delay organs damage in CS. We hypothesize that cytidine-5-diphosphocholine (CDP-choline) can act as a cytoprotective pharmacological measure that diminishes the target organ damage.

Apr 2, 2024 | karger.com | Newby LK

Background: The use of cell salvage and autologous blood transfusion is an important and widespread method of blood conservation during surgeries with expected high blood loss. The continuous autotransfusion device CATSmart® (Fresenius Kabi, Germany) contains two new washing programs on the device called Flex wash 3 and Flex wash 5. To the best of our knowledge, there are no published clinical data regarding the performance of the two new washing programs.